Optimization of the freeze-drying process for microemulsion systems
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چکیده
منابع مشابه
PAT Tools for the Optimization of the Freeze-Drying Process
1. Freezing: the product to be dried is put over shelves in a chamber and its temperature is lowered so that the water (or the other solvent) is frozen. Unfortunately, not all the solvent freezes forming ice crystals, but a certain amount (sometimes significant) remains bonded to the product and must be finally desorbed. In some cases the product (the drug and the excipients) does not crystalli...
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Freeze-drying has been considered as a good technique to improve the long-term stability of colloidal nanoparticles. The poor stability in an aqueous medium of these systems forms a real barrier against the clinical use of nanoparticles. This article reviews the state of the art of freeze-drying nanoparticles. It discusses the most important parameters that influence the success of freeze-dryin...
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ژورنال
عنوان ژورنال: Drying Technology
سال: 2018
ISSN: 0737-3937,1532-2300
DOI: 10.1080/07373937.2018.1536883